Gilbert Di Paolo Selected Research

Phosphatidic Acids (Phosphatidic Acid)

1/2019	Phosphatidic acid generated by PLD2 promotes the plasma membrane recruitment of IQGAP1 and neointima formation.
1/2019	Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis.
10/2017	Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells.
8/2010	Phospholipase D in brain function and Alzheimer's disease.

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Gilbert Di Paolo Research Topics

Disease

17	Alzheimer Disease (Alzheimer's Disease) 11/2022 - 12/2006
6	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2018 - 05/2011
3	Down Syndrome (Down's Syndrome) 01/2018 - 07/2008
3	Neoplasms (Cancer) 10/2017 - 11/2012
2	Neointima 01/2022 - 01/2019
2	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2022 - 12/2012
2	Atherosclerosis 01/2018 - 01/2016
2	Amyloid Plaque 12/2017 - 11/2017
2	Neoplasm Metastasis (Metastasis) 10/2017 - 11/2012
2	Parkinsonian Disorders (Parkinsonism) 04/2015 - 09/2013
1	Vascular Diseases (Vascular Disease) 01/2022
1	Sepsis (Septicemia) 01/2021
1	Frontotemporal Dementia (Semantic Dementia) 01/2021
1	Multiple Sclerosis 01/2021
1	Osteosarcoma (Osteogenic Sarcoma) 01/2020
1	Central Nervous System Diseases (CNS Diseases) 01/2020
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2020
1	Mucopolysaccharidosis II (Hunter Syndrome) 01/2020
1	Neuroinflammatory Diseases 01/2020
1	Demyelinating Diseases (Demyelinating Disease) 01/2020
1	Pathologic Processes 01/2019
1	Vascular System Injuries 01/2019
1	Fibrosis (Cirrhosis) 01/2019
1	Hyperplasia 01/2019
1	Nervous System Diseases (Neurological Disorders) 01/2019
1	Pneumonia (Pneumonitis) 01/2019
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2019
1	Infarction (Infarctions) 05/2018
1	Hypertrophy 05/2018
1	Memory Disorders (Memory Loss) 01/2018
1	Atherosclerotic Plaque (Atheroma) 01/2018
1	Breast Neoplasms (Breast Cancer) 10/2017
1	Body Weight (Weight, Body) 01/2017
1	Weight Gain 01/2017
1	Insulin Resistance 01/2017
1	Obesity 01/2017
1	Parkinson Disease (Parkinson's Disease) 01/2017
1	Non-alcoholic Fatty Liver Disease 12/2016
1	Dyslipidemias (Dyslipidemia) 10/2016
1	Congenital Structural Myopathies (Centronuclear Myopathy) 01/2016
1	Fatty Liver 01/2016
1	Colitis 07/2015
1	Colorectal Neoplasms (Colorectal Cancer) 07/2015
1	Colonic Neoplasms (Colon Cancer) 07/2015
1	Carcinoma (Carcinomatosis) 07/2015
1	Carcinogenesis 07/2015

Drug/Important Bio-Agent (IBA)

13	LipidsIBA 01/2021 - 08/2010
6	Amyloid (Amyloid Fibrils)IBA 12/2017 - 10/2012
6	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2016 - 07/2003
5	1-dodecylpyridoxal (PLD)IBA 01/2022 - 01/2010
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 04/2015
4	EnzymesIBA 01/2020 - 08/2010
4	Phosphatidic Acids (Phosphatidic Acid)IBA 01/2019 - 08/2010
4	synaptojaninIBA 01/2018 - 07/2008
4	Peptides (Polypeptides)IBA 12/2017 - 10/2012
4	phospholipase D1IBA 12/2016 - 01/2010
3	Phospholipase DIBA 01/2019 - 08/2010
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 01/2019
2	ProgranulinsIBA 01/2022 - 01/2021
2	Flavin-Adenine Dinucleotide (FAD)IBA 01/2018 - 12/2006
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 12/2017 - 11/2017
2	phospholipase D2IBA 10/2017 - 12/2010
2	SynucleinsIBA 01/2017 - 04/2015
2	Triglycerides (Triacylglycerol)IBA 12/2016 - 10/2016
2	Transcription Factors (Transcription Factor)IBA 01/2016 - 12/2012
2	CholesterolIBA 01/2016 - 05/2011
1	Apolipoprotein E4IBA 01/2022
1	AntibodiesIBA 01/2022
1	ApolipoproteinsIBA 01/2022
1	CardiotoxinsIBA 01/2021
1	Small Interfering RNA (siRNA)IBA 01/2020
1	Phospholipases (Phospholipase)IBA 01/2020
1	Iduronic Acid (Iduronate)IBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	indium-bleomycinIBA 01/2019
1	Mitochondrial DNA (mtDNA)IBA 01/2019
1	GlucocorticoidsIBA 01/2019
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2019
1	HydrogelsIBA 05/2018
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	SynaptophysinIBA 01/2018
1	oxidized low density lipoproteinIBA 01/2018
1	Matrix Metalloproteinase 14 (MT1-MMP)IBA 10/2017
1	Glucose (Dextrose)FDA LinkGeneric 01/2017
1	Steroid 12-alpha-Hydroxylase (CYP8B1)IBA 01/2017
1	Apolipoproteins B (ApoB)IBA 10/2016
1	Bile Acids and Salts (Bile Acids)IBA 01/2016
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2016
1	LDL Receptors (LDL Receptor)IBA 01/2016
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2016
1	HDL LipoproteinsIBA 01/2016
1	Liver X ReceptorsIBA 01/2016
1	AzoxymethaneIBA 07/2015
1	Dextrans (Dextran)FDA Link 07/2015
1	MicroRNAs (MicroRNA)IBA 07/2015
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 07/2015

Therapy/Procedure

5	Therapeutics 11/2022 - 11/2012
1	Ligation 01/2022
1	Enzyme Therapy 01/2020
1	Fat-Restricted Diet (Diet, Fat Restricted) 01/2017